Alyssa Milano is separating from Mistresses. Yep, the ABC drama will be down one leading lady when it returns for its recently announced season three. The former Charmed star shared the news on social media, posting to both Facebook and Twitter. Milano wrote, “After two wonderful seasons in Los Angeles, the studio has decided to shoot season three of Mistresses in Vancouver, Canada, for financial reasons. It’s with a heavy heart that I have decided that I can’t relocate.