Are Alex (Justin Chambers) and Meredith (Ellen Pompeo) Meant For Each Other on ABC’s Grey’s Anatomy? Since Derek’s death — and the year-plus that has passed in the two episodes since leading man Patrick Dempsey’s shocking exit — diehard fans of the ABC medical drama have become increasingly vocal and wondering if two of the show’s remaining original characters should wind up together. Except there’s just one problem: Alex’s longtime girlfriend, Jo (Camilla Luddington). “It’s Shondaland, anything can happen!” co-star Luddington tells The Hollywood Reporter of the idea of pairing Meredith and Alex together. “But what’s really nice about Alex and Meredith is we’re seeing a very platonic relationship … it doesn’t have to be sexual and they can love each other in a way that’s really deep, ” She said.